Taking over Cambodia's 121,405-sq-meter private island of Krabey, Six Senses Krabey Island is as striking and exotic as they come.

Set to open this December, the resort’s 40 private pool villas enjoy tropical surrounds and sleek modern designs. Inside, natural materials—teakwood, bamboo, weaving—support a raw and organic feel that belies the decidedly high-tech comforts of the facilities. Rates for the 118 sq-meter Hideaway Pool Villa start from B21,838 a night.

Despite being buried in the depths of the forest on an as yet almost untouched island, the facilities are extensive, ranging from an open-air cinema, meditation cave and rooftop yoga pavilion, to jungle fitness classes and a spa inspired by the ancient Khmer Kbal Spean River, offering holistic wellness and rejuvenation treatments. Activities for adventurers are also on offer, including fishing, snorkeling and a night sky observatory for stargazing.

The resort’s mainland reception is a 10-minute drive from Sihanouk International Airport—served by flights from Phnom Penh, Siem Reap, Ho Chi Minh City and Kuala Lumpur—while the island is a further 15 minute cruise away by boat. The resort is also within five-kilometers of Ream National Park.